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Metal Free Sequential [3+2]-Dipolar Cycloadditions using Cyclooctynes and 1,3-Dipoles of Different Reactivity

Although metal free cycloadditions of cyclooctynes and azides to give stable 1,2,3-triazoles have found wide utility in chemical biology and material sciences, there is an urgent need for faster and more versatile bioorthogonal reactions. We have found that nitrile oxides and diazocarbonyl derivativ...

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Dettagli Bibliografici
Autori principali: Sanders, Brian C., Friscourt, Frédéric, Ledin, Petr A., Mbua, Ngalle Eric, Arumugam, Selvanathan, Guo, Jun, Boltje, Thomas J., Popik, Vladimir V., Boons, Geert-Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079482/
https://ncbi.nlm.nih.gov/pubmed/21182329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1081519
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