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Metal Free Sequential [3+2]-Dipolar Cycloadditions using Cyclooctynes and 1,3-Dipoles of Different Reactivity

Although metal free cycloadditions of cyclooctynes and azides to give stable 1,2,3-triazoles have found wide utility in chemical biology and material sciences, there is an urgent need for faster and more versatile bioorthogonal reactions. We have found that nitrile oxides and diazocarbonyl derivativ...

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Detalhes bibliográficos
Main Authors: Sanders, Brian C., Friscourt, Frédéric, Ledin, Petr A., Mbua, Ngalle Eric, Arumugam, Selvanathan, Guo, Jun, Boltje, Thomas J., Popik, Vladimir V., Boons, Geert-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079482/
https://ncbi.nlm.nih.gov/pubmed/21182329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1081519
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