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The gastric HK-ATPase: structure, function, and inhibition
The gastric H,K-ATPase, a member of the P(2)-type ATPase family, is the integral membrane protein responsible for gastric acid secretion. It is an α,β-heterodimeric enzyme that exchanges cytoplasmic hydronium with extracellular potassium. The catalytic α subunit has ten transmembrane segments with a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079481/ https://ncbi.nlm.nih.gov/pubmed/18536934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-008-0495-4 |
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