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The gastric HK-ATPase: structure, function, and inhibition

The gastric H,K-ATPase, a member of the P(2)-type ATPase family, is the integral membrane protein responsible for gastric acid secretion. It is an α,β-heterodimeric enzyme that exchanges cytoplasmic hydronium with extracellular potassium. The catalytic α subunit has ten transmembrane segments with a...

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Detalhes bibliográficos
Main Authors: Shin, Jai Moo, Munson, Keith, Vagin, Olga, Sachs, George
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079481/
https://ncbi.nlm.nih.gov/pubmed/18536934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-008-0495-4
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