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Novel Approaches to Inhibition of Gastric Acid Secretion
The gastric H,K-adenosine triphosphatase (ATPase) is the primary target for treatment of acid-related diseases. Proton pump inhibitors (PPIs) are weak bases composed of two moieties, a substituted pyridine with a primary pK(a) of about 4.0 that allows selective accumulation in the secretory canalicu...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Current Science Inc.
2010
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974194/ https://ncbi.nlm.nih.gov/pubmed/20924727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11894-010-0149-5 |
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