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Activity-Dependent Ubiquitination of GluA1 Mediates a Distinct AMPA Receptor Endocytosis and Sorting Pathway

The accurate trafficking of AMPA receptors (AMPARs) to and from the synapse is a critical component of learning and memory in the brain, whereas dysfunction of AMPAR trafficking is hypothesized to be an underlying mechanism of Alzheimer's disease. Previous work has shown that ubiquitination of...

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Autori principali: Schwarz, Lindsay A., Hall, Benjamin J., Patrick, Gentry N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079366/
https://ncbi.nlm.nih.gov/pubmed/21148011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3686-10.2010
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