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Neurobiological effects of sphingosine 1-phosphate receptor modulation in the cuprizone model

Fingolimod (FTY720) is a sphingosine 1-phosphate (S1P) receptor modulator that regulates lymphocyte trafficking and exerts pleiotropic actions on oligodendrocytes (OLGs) and other neural cells. The purpose of this study was to investigate the role of S1P receptors in a non-T-cell model of demyelinat...

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Autors principals: Kim, Hye Jung, Miron, Veronique E., Dukala, Danuta, Proia, Richard L., Ludwin, Samuel K., Traka, Maria, Antel, Jack P., Soliven, Betty
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079302/
https://ncbi.nlm.nih.gov/pubmed/21248243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-173203
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