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Fingolimod (FTY720) Enhances Remyelination Following Demyelination of Organotypic Cerebellar Slices

Remyelination, which occurs subsequent to demyelination, contributes to functional recovery and is mediated by oligodendrocyte progenitor cells (OPCs) that have differentiated into myelinating cells. Therapeutics that impact remyelination in the CNS could be critical determinants of long-term functi...

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Detalhes bibliográficos
Main Authors: Miron, Veronique E., Ludwin, Samuel K., Darlington, Peter J., Jarjour, Andrew A., Soliven, Betty, Kennedy, Timothy E., Antel, Jack P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877831/
https://ncbi.nlm.nih.gov/pubmed/20413685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091234
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