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Cyclical and Dose-Dependent Responses of Adult Human Mature Oligodendrocytes to Fingolimod
Fingolimod is a sphingosine-1-phosphate (S1P) analogue that has been used in clinical trials as a systemic immunomodulatory therapy for multiple sclerosis. Fingolimod readily accesses the central nervous system, raising the issue of its direct effects on neural cells. We assessed the effects of acti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2543081/ https://ncbi.nlm.nih.gov/pubmed/18772343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080478 |
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