Statin Therapy Inhibits Remyelination in the Central Nervous System

Remyelination of lesions in the central nervous system contributes to neural repair following clinical relapses in multiple sclerosis. Remyelination is initiated by recruitment and differentiation of oligodendrocyte progenitor cells (OPCs) into myelinating oligodendrocytes. Simvastatin, a blood-brai...

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Detalhes bibliográficos
Main Authors: Miron, Veronique E., Zehntner, Simone P., Kuhlmann, Tanja, Ludwin, Samuel K., Owens, Trevor, Kennedy, Timothy E., Bedell, Barry J., Antel, Jack P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671276/
https://ncbi.nlm.nih.gov/pubmed/19349355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080947
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