Statin Therapy Inhibits Remyelination in the Central Nervous System

Remyelination of lesions in the central nervous system contributes to neural repair following clinical relapses in multiple sclerosis. Remyelination is initiated by recruitment and differentiation of oligodendrocyte progenitor cells (OPCs) into myelinating oligodendrocytes. Simvastatin, a blood-brai...

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Bibliographische Detailangaben
Hauptverfasser: Miron, Veronique E., Zehntner, Simone P., Kuhlmann, Tanja, Ludwin, Samuel K., Owens, Trevor, Kennedy, Timothy E., Bedell, Barry J., Antel, Jack P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2009
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671276/
https://ncbi.nlm.nih.gov/pubmed/19349355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080947
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