Statin Therapy Inhibits Remyelination in the Central Nervous System

Remyelination of lesions in the central nervous system contributes to neural repair following clinical relapses in multiple sclerosis. Remyelination is initiated by recruitment and differentiation of oligodendrocyte progenitor cells (OPCs) into myelinating oligodendrocytes. Simvastatin, a blood-brai...

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Autors principals: Miron, Veronique E., Zehntner, Simone P., Kuhlmann, Tanja, Ludwin, Samuel K., Owens, Trevor, Kennedy, Timothy E., Bedell, Barry J., Antel, Jack P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2009
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671276/
https://ncbi.nlm.nih.gov/pubmed/19349355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080947
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