Fingolimod (FTY720) Enhances Remyelination Following Demyelination of Organotypic Cerebellar Slices

Remyelination, which occurs subsequent to demyelination, contributes to functional recovery and is mediated by oligodendrocyte progenitor cells (OPCs) that have differentiated into myelinating cells. Therapeutics that impact remyelination in the CNS could be critical determinants of long-term functi...

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Hlavní autoři: Miron, Veronique E., Ludwin, Samuel K., Darlington, Peter J., Jarjour, Andrew A., Soliven, Betty, Kennedy, Timothy E., Antel, Jack P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877831/
https://ncbi.nlm.nih.gov/pubmed/20413685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091234
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