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Conformational studies of the robust 2-Cys peroxiredoxin Salmonella typhimurium AhpC by solution phase hydrogen/deuterium (H/D) exchange monitored by electrospray ionization mass spectrometry

This is the first comprehensive HX-MS study of a “robust” 2-Cys peroxiredoxin (Prx), namely Salmonella typhimurium AhpC (StAhpC). Prx proteins control intracellular peroxide levels and are abundant antioxidant proteins in eukaryotes, archaea and bacteria. Crystal structural analyses and structure/ac...

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Detalhes bibliográficos
Main Authors: Nirudodhi, Sasidhar, Parsonage, Derek, Karplus, P. Andrew, Poole, Leslie B., Maier, Claudia S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079231/
https://ncbi.nlm.nih.gov/pubmed/21516234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2010.08.018
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