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Broad specificity AhpC-like peroxiredoxin and its thioredoxin reductant in the sparse antioxidant defense system of Treponema pallidum

Little is known about the mechanisms by which Treponema pallidum (Tp), the causative agent of syphilis, copes with oxidative stress as it establishes persistent infection within its obligate human host. The Tp genomic sequence indicates that the bacterium’s antioxidant defenses do not include glutat...

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Autores principales: Parsonage, Derek, Desrosiers, Daniel C., Hazlett, Karsten R. O., Sun, Yongcheng, Nelson, Kimberly J., Cox, David L., Radolf, Justin D., Poole, Leslie B.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851974/
https://ncbi.nlm.nih.gov/pubmed/20304799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910057107
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