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Multiple elements in human beta-globin locus control region 5' HS 2 are involved in enhancer activity and position-independent, transgene expression.

The human beta-globin Locus Control Region (LCR) has two important activities. First, the LCR opens a 200 kb chromosomal domain containing the human epsilon-, gamma- and beta-globin genes and, secondly, these sequences function as a powerful enhancer of epsilon-, gamma- and beta-globin gene expressi...

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Main Authors: Caterina, J J, Ciavatta, D J, Donze, D, Behringer, R R, Townes, T M
格式: Artigo
語言:Inglês
出版: 1994
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC307922/
https://ncbi.nlm.nih.gov/pubmed/8152905
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