Multiple elements in human beta-globin locus control region 5' HS 2 are involved in enhancer activity and position-independent, transgene expression.

The human beta-globin Locus Control Region (LCR) has two important activities. First, the LCR opens a 200 kb chromosomal domain containing the human epsilon-, gamma- and beta-globin genes and, secondly, these sequences function as a powerful enhancer of epsilon-, gamma- and beta-globin gene expressi...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Caterina, J J, Ciavatta, D J, Donze, D, Behringer, R R, Townes, T M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1994
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307922/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8152905/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.6.1006
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