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Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107.

Cyclins, TFIIB and RB play major roles in cell cycle and/or gene regulation. Earlier work has suggested common ancestry for the TFIIB repeats and RB pocket B which share 20% sequence identity. We now report that database searches with profiles based on a multiple alignment of cyclin core regions (th...

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Detalhes bibliográficos
Main Authors: Gibson, T J, Thompson, J D, Blocker, A, Kouzarides, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC307913/
https://ncbi.nlm.nih.gov/pubmed/8152925
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