Inhibition of Oesophageal Squamous Cell Carcinoma Progression by in vivo Targeting of Hyaluronan Synthesis

BACKGROUND: Oesophageal cancer is a highly aggressive tumour entity with at present poor prognosis. Therefore, novel treatment options are urgently needed. Hyaluronan (HA) is a polysaccharide present in the matrix of human oesophageal squamous cell carcinoma (ESCC). Importantly, in vitro ESCC cells...

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Hauptverfasser: Twarock, Sören, Freudenberger, Till, Poscher, Eva, Dai, Guang, Jannasch, Katharina, Dullin, Christian, Alves, Frauke, Prenzel, Klaus, Knoefel, Wolfram T, Stoecklein, Nikolas H, Savani, Rashmin C, Homey, Bernhard, Fischer, Jens W
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078897/
https://ncbi.nlm.nih.gov/pubmed/21429221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-30
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