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Cortical localization of APC2 plays a role in actin organization but not in Wnt signaling in Drosophila

The tumor suppressor Adenomatous polyposis coli (APC) has roles in both Wnt signaling and in actin and microtubule organization. Within the cell, APC proteins have been reported to localize in the cytoplasm, at the cell cortex and in the nucleus. How these localizations relate to the functions of th...

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Autors principals: Zhou, Meng-Ning, Kunttas-Tatli, Ezgi, Zimmerman, Sandra, Zhouzheng, Fangyuan, McCartney, Brooke M.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078822/
https://ncbi.nlm.nih.gov/pubmed/21486956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.073916
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