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Cortical localization of APC2 plays a role in actin organization but not in Wnt signaling in Drosophila

The tumor suppressor Adenomatous polyposis coli (APC) has roles in both Wnt signaling and in actin and microtubule organization. Within the cell, APC proteins have been reported to localize in the cytoplasm, at the cell cortex and in the nucleus. How these localizations relate to the functions of th...

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Detalhes bibliográficos
Main Authors: Zhou, Meng-Ning, Kunttas-Tatli, Ezgi, Zimmerman, Sandra, Zhouzheng, Fangyuan, McCartney, Brooke M.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078822/
https://ncbi.nlm.nih.gov/pubmed/21486956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.073916
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