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Activation of the aryl hydrocarbon receptor by doxorubicin mediates cytoprotective effects in the heart
AIMS: Doxorubicin (DOX) is a highly effective chemotherapeutic agent; however, cumulative dose-dependent cardiotoxicity is a significant side effect of this therapy. Because DOX is a polyaromatic hydrocarbon, we hypothesized that it will be metabolized by the activation of the aryl hydrocarbon recep...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078799/ https://ncbi.nlm.nih.gov/pubmed/21233252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr007 |
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