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Role of GAC63 in transcriptional activation mediated by the aryl hydrocarbon receptor

The aryl hydrocarbon receptor (AHR), a member of the basic helix-loop-helix/Per-Arnt-Sim (bHLH-PAS) gene family, binds a variety of polycyclic aromatic hydrocarbons and mediates their toxic effects. GAC63 has been shown to act as a coactivator in nuclear receptor (NR) mediated gene transcription. In...

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Detalhes bibliográficos
Main Authors: Chen, Yong-Heng, Beischlag, Timothy V., Kim, Jeong Hoon, Perdew, Gary H., Stallcup, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770942/
https://ncbi.nlm.nih.gov/pubmed/16513642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M512537200
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