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Incorporation of (R)- and (S)-3',4'-seco-thymidine into oligodeoxynucleotides: hybridization properties and enzymatic stability.

Novel flexible oligodeoxynucleotide analogues containing (R)- and (S)-3',4'-seco-thymidine were synthesized on an automated DNA-synthesizer using the phosphoramidite approach. Oligodeoxynucleotide analogues (17-mers) having one or three modifications in the middle or one or two modificatio...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Nielsen, P, Kirpekar, F, Wengel, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1994
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307872/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8139908/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.5.703
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