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Incorporation of hexose nucleoside analogues into oligonucleotides: synthesis, base-pairing properties and enzymatic stability.

Oligonucleotides containing 1-(2,4-dideoxy-beta-D-erythro-hexopyranosyl)thymine (2) and 1-(3,4-dideoxy-beta-D-erythro-hexopyranosyl)thymine (3) were synthesized on a solid support using the phosphoramidite approach. The properties of these oligonucleotides were compared with the earlier reported cha...

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Detalhes bibliográficos
Main Authors: Augustyns, K, Vandendriessche, F, Van Aerschot, A, Busson, R, Urbanke, C, Herdewijn, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC334221/
https://ncbi.nlm.nih.gov/pubmed/1329028
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