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Oxidative stress mediates nephropathy in type Ia glycogen storage disease
Glycogen storage disease type Ia (GSD-Ia) patients, deficient in glucose-6-phosphatase-α, manifest disturbed glucose homeostasis with long-term renal disease. We have previously shown that renal fibrosis in GSD-Ia is mediated by the angiotensin/transforming growth factor-β1 (TGF-β1) pathway which al...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078689/ https://ncbi.nlm.nih.gov/pubmed/20195241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.38 |
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