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Oxidative stress mediates nephropathy in type Ia glycogen storage disease

Glycogen storage disease type Ia (GSD-Ia) patients, deficient in glucose-6-phosphatase-α, manifest disturbed glucose homeostasis with long-term renal disease. We have previously shown that renal fibrosis in GSD-Ia is mediated by the angiotensin/transforming growth factor-β1 (TGF-β1) pathway which al...

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Detalhes bibliográficos
Main Authors: Yiu, Wai Han, Mead, Paul A., Jun, Hyun Sik, Mansfield, Brian C., Chou, Janice Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078689/
https://ncbi.nlm.nih.gov/pubmed/20195241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.38
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