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Development of Calorie Restriction Mimetics as Therapeutics for Obesity, Diabetes, Inflammatory and Neurodegenerative Diseases

Calorie restriction (CR) is the most robust intervention that decreases morbidity and mortality, and thereby increases the lifespan of many organisms. Although the signaling pathways involved in the beneficial effects of CR are not yet fully understood. Several candidate pathways and key molecules h...

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Autors principals: Chiba, Takuya, Tsuchiya, Tomoshi, Komatsu, Toshimitsu, Mori, Ryoichi, Hayashi, Hiroko, Shimokawa, Isao
Format: Artigo
Idioma:Inglês
Publicat: Bentham Science Publishers Ltd 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078680/
https://ncbi.nlm.nih.gov/pubmed/21629433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920210793360934
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