On the rapid deprotection of synthetic oligonucleotides and analogs.
The efficiency of oligodeoxynucleotide deprotection is greatly enhanced using a combination of: (a) ethanolamine, and especially a mixture of hydrazine, ethanolamine and methanol, in place of the usual aqueous ammonia; (b) tert-butylphenoxyacetyl amino protecting groups, and (c) oxalyl link between...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1994
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| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307855/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127712/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.4.639 |
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