Somatic Mutations of PPP2R1A in Ovarian and Uterine Carcinomas

Exome sequencing of ovarian clear-cell carcinoma has identified somatic mutations in PPP2R1A, a subunit of protein phosphatase 2A. The present study was performed to determine the frequency of PPP2R1A mutations in exon 5, which harbors previously reported mutation hot spots, and adjacent exon 6, in...

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Main Authors: Shih, Ie-Ming, Panuganti, Pradeep K., Kuo, Kuan-Tin, Mao, Tsui-Lien, Kuhn, Elisabetta, Jones, Sian, Velculescu, Victor E., Kurman, Robert J., Wang, Tian-Li
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2011
Teme:
Short Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078449/
https://ncbi.nlm.nih.gov/pubmed/21435433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.009
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