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Somatic Mutations of PPP2R1A in Ovarian and Uterine Carcinomas

Exome sequencing of ovarian clear-cell carcinoma has identified somatic mutations in PPP2R1A, a subunit of protein phosphatase 2A. The present study was performed to determine the frequency of PPP2R1A mutations in exon 5, which harbors previously reported mutation hot spots, and adjacent exon 6, in...

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Detalhes bibliográficos
Main Authors: Shih, Ie-Ming, Panuganti, Pradeep K., Kuo, Kuan-Tin, Mao, Tsui-Lien, Kuhn, Elisabetta, Jones, Sian, Velculescu, Victor E., Kurman, Robert J., Wang, Tian-Li
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078449/
https://ncbi.nlm.nih.gov/pubmed/21435433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.009
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