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Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart

Identification of genomic regions that control tissue-specific gene expression is currently problematic. ChIP and high-throughput sequencing (ChIP-seq) of enhancer-associated proteins such as p300 identifies some but not all enhancers active in a tissue. Here we show that co-occupancy of a chromatin...

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Detalhes bibliográficos
Main Authors: He, Aibin, Kong, Sek Won, Ma, Qing, Pu, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078411/
https://ncbi.nlm.nih.gov/pubmed/21415370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016959108
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