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Cell cycle restriction by histone H2AX limits proliferation of adult neural stem cells
Adult neural stem cell proliferation is dynamic and has the potential for massive self-renewal yet undergoes limited cell division in vivo. Here, we report an epigenetic mechanism regulating proliferation and self-renewal. The recruitment of the PI3K-related kinase signaling pathway and histone H2AX...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078396/ https://ncbi.nlm.nih.gov/pubmed/21436033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014993108 |
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