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Disrupted-in-Schizophrenia 1–mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling

Defects in neuronal connectivity of the brain are well documented among schizophrenia patients. Although the schizophrenia susceptibility gene Disrupted-in-Schizophrenia 1 (DISC1) has been implicated in various neurodevelopmental processes, its role in regulating axonal connections remains elusive....

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Detalhes bibliográficos
Main Authors: Chen, Shih-Yu, Huang, Pei-Hsin, Cheng, Hwai-Jong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078365/
https://ncbi.nlm.nih.gov/pubmed/21422296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018128108
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