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Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK

The small GTPase Rac regulates cytoskeletal organization, cell cycle progression, gene expression and oncogenic transformation, processes that depend upon both soluble growth factors and adhesion to the extracellular matrix (ECM). We now show that growth factors and adhesion to the ECM both contribu...

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Detalhes bibliográficos
Main Authors: del Pozo, Miguel A., Price, Leo S., Alderson, Nazilla B., Ren, Xiang-Dong, Schwartz, Martin Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305684/
https://ncbi.nlm.nih.gov/pubmed/10790367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.9.2008
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