Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK

The small GTPase Rac regulates cytoskeletal organization, cell cycle progression, gene expression and oncogenic transformation, processes that depend upon both soluble growth factors and adhesion to the extracellular matrix (ECM). We now show that growth factors and adhesion to the ECM both contribu...

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Bibliographic Details
Main Authors: del Pozo, Miguel A., Price, Leo S., Alderson, Nazilla B., Ren, Xiang-Dong, Schwartz, Martin Alexander
Format: Artigo
Language:Inglês
Published: Oxford University Press 2000
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC305684/
https://ncbi.nlm.nih.gov/pubmed/10790367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.9.2008
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