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Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells
Mutations in the IL23R gene are linked to inflammatory bowel disease susceptibility. Experimental models have shown that interleukin-23 (IL-23) orchestrates innate and T cell-dependent colitis; however, the cell populations it acts on to induce intestinal immune pathology are unknown. Here, using Il...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cell Press
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078329/ https://ncbi.nlm.nih.gov/pubmed/20732640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.08.010 |
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