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Innate lymphoid cells drive IL-23 dependent innate intestinal pathology

The key role of IL-23 in the pathogenesis of autoimmune and chronic inflammatory disorders is supported by the identification of IL-23R susceptibility alleles associated with IBD, psoriasis and ankylosing spondylitis. IL-23 driven inflammation has primarily been linked to the actions of Th17 cells(1...

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Autors principals: Buonocore, Sofia, Ahern, Philip P., Uhlig, Holm H., Ivanov, Ivaylo I., Littman, Dan R., Maloy, Kevin J., Powrie, Fiona
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796764/
https://ncbi.nlm.nih.gov/pubmed/20393462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08949
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