A Critical Role for GRP78/BiP in the Tumor Microenvironment for Neovascularization During Tumor Growth and Metastasis

GRP78/BiP is a multifunctional protein which plays a major role in endoplasmic reticulum (ER) protein processing, protein quality control, maintaining ER homeostasis and controlling cell signaling and viability. Previously, using a transgene-induced mammary tumor model, we demonstrated that Grp78 he...

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Bibliographische Detailangaben
Hauptverfasser: Dong, Dezheng, Stapleton, Christopher, Luo, Biquan, Xiong, Shigang, Ye, Wei, Zhang, Yi, Jhaveri, Niyati, Zhu, Genyuan, Ye, Risheng, Liu, Zhi, Bruhn, Kevin W., Craft, Noah, Groshen, Susan, Hofman, Florence M., Lee, Amy S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078191/
https://ncbi.nlm.nih.gov/pubmed/21467168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3151
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