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Renal (pro)renin receptor contributes to development of diabetic kidney disease through TGFβ1-CTGF signaling cascade

1. Transforming growth factor β1 (TGFβ1) and connective tissue growth factor (CTGF) are expressed in renal glomeruli and contribute to development of diabetic nephropathy. Recently we demonstrated that (pro)renin receptor (PRR) is upregulated in the kidneys of streptozocin (STZ)-induced diabetes rat...

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Hlavní autoři: Huang, Jiqian, Matavelli, Luis C., Siragy, Helmy M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077929/
https://ncbi.nlm.nih.gov/pubmed/21265872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1440-1681.2011.05486.x
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