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A Re-wired Green Fluorescent Protein: Folding and Function in a Non-sequential, Non-circular GFP Permutant

The sequential order of secondary structural elements in proteins affects the folding and activity to an unknown extent. To test the dependence on sequential connectivity, secondary structural elements were reconnected by their solvent-exposed ends, permuting their sequential order, called “re-wirin...

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Detalhes bibliográficos
Main Authors: Reeder, Philippa J., Huang, Yao-Ming, Dordick, Jonathan S., Bystroff, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077829/
https://ncbi.nlm.nih.gov/pubmed/21090791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100975z
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