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A Re-wired Green Fluorescent Protein: Folding and Function in a Non-sequential, Non-circular GFP Permutant

The sequential order of secondary structural elements in proteins affects the folding and activity to an unknown extent. To test the dependence on sequential connectivity, secondary structural elements were reconnected by their solvent-exposed ends, permuting their sequential order, called “re-wirin...

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Hlavní autoři: Reeder, Philippa J., Huang, Yao-Ming, Dordick, Jonathan S., Bystroff, Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077829/
https://ncbi.nlm.nih.gov/pubmed/21090791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100975z
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