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Phosphorylation regulates c-Myc’s oncogenic activity in the mammary gland

Expression of the c-Myc oncoprotein is affected by conserved Threonine 58 (T58) and Serine 62 (S62) phosphorylation sites that help to regulate c-Myc protein stability, and altered ratios of T58 and S62 phosphorylation have been observed in human cancer. Here, we report the development of three uniq...

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Autors principals: Wang, Xiaoyan, Cunningham, Melissa, Zhang, Xiaoli, Tokarz, Sara, Laraway, Bryan, Troxell, Megan, Sears, Rosalie C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077809/
https://ncbi.nlm.nih.gov/pubmed/21266350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1032
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