טוען...
Novel Role of Base Excision Repair in Mediating Cisplatin Cytotoxicity
Using isogenic mouse embryonic fibroblasts and human cancer cell lines, we show that cells defective in base excision repair (BER) display a cisplatin-specific resistant phenotype. This was accompanied by enhanced repair of cisplatin interstrand cross-links (ICLs) and ICL-induced DNA double strand b...
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| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077654/ https://ncbi.nlm.nih.gov/pubmed/21357694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.225375 |
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