Liver X Receptor-Retinoid X Receptor (LXR-RXR) Heterodimer Cistrome Reveals Coordination of LXR and AP1 Signaling in Keratinocytes

Liver X receptors (LXRs) play a critical role in regulating lipid synthesis and transport in numerous tissues. In the skin, activation of LXR induces keratinocyte differentiation and improves epidermal permeability barrier homeostasis. To elucidate the mechanism of LXR action in skin, we mapped its...

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Detalles Bibliográficos
Main Authors: Shen, Qi, Bai, Yuchen, Chang, Ken C. N., Wang, Yongjun, Burris, Thomas P., Freedman, Leonard P., Thompson, Catherine C., Nagpal, Sunil
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Gene Regulation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077653/
https://ncbi.nlm.nih.gov/pubmed/21349840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165704
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