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Ligand modulates the conversion of DNA-bound vitamin D3 receptor (VDR) homodimers into VDR-retinoid X receptor heterodimers.

Protein dimerization facilitates cooperative, high-affinity interactions with DNA. Nuclear hormone receptors, for example, bind either as homodimers or as heterodimers with retinoid X receptors (RXR) to half-site repeats that are stabilized by protein-protein interactions mediated by residues within...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Cheskis, B, Freedman, L P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 1994
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358699/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8164684/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.5.3329-3338.1994
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