Liver X Receptor-Retinoid X Receptor (LXR-RXR) Heterodimer Cistrome Reveals Coordination of LXR and AP1 Signaling in Keratinocytes

Liver X receptors (LXRs) play a critical role in regulating lipid synthesis and transport in numerous tissues. In the skin, activation of LXR induces keratinocyte differentiation and improves epidermal permeability barrier homeostasis. To elucidate the mechanism of LXR action in skin, we mapped its...

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Dades bibliogràfiques
Autors principals: Shen, Qi, Bai, Yuchen, Chang, Ken C. N., Wang, Yongjun, Burris, Thomas P., Freedman, Leonard P., Thompson, Catherine C., Nagpal, Sunil
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077653/
https://ncbi.nlm.nih.gov/pubmed/21349840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165704
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