Liver X Receptor-Retinoid X Receptor (LXR-RXR) Heterodimer Cistrome Reveals Coordination of LXR and AP1 Signaling in Keratinocytes

Liver X receptors (LXRs) play a critical role in regulating lipid synthesis and transport in numerous tissues. In the skin, activation of LXR induces keratinocyte differentiation and improves epidermal permeability barrier homeostasis. To elucidate the mechanism of LXR action in skin, we mapped its...

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Hlavní autoři: Shen, Qi, Bai, Yuchen, Chang, Ken C. N., Wang, Yongjun, Burris, Thomas P., Freedman, Leonard P., Thompson, Catherine C., Nagpal, Sunil
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077653/
https://ncbi.nlm.nih.gov/pubmed/21349840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165704
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