Liver X Receptor-Retinoid X Receptor (LXR-RXR) Heterodimer Cistrome Reveals Coordination of LXR and AP1 Signaling in Keratinocytes

Liver X receptors (LXRs) play a critical role in regulating lipid synthesis and transport in numerous tissues. In the skin, activation of LXR induces keratinocyte differentiation and improves epidermal permeability barrier homeostasis. To elucidate the mechanism of LXR action in skin, we mapped its...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shen, Qi, Bai, Yuchen, Chang, Ken C. N., Wang, Yongjun, Burris, Thomas P., Freedman, Leonard P., Thompson, Catherine C., Nagpal, Sunil
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077653/
https://ncbi.nlm.nih.gov/pubmed/21349840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165704
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