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The Anti-angiogenic Peptide Anginex Greatly Enhances Galectin-1 Binding Affinity for Glycoproteins

Angiogenesis is a key event in cancer progression and therefore a promising target in cancer treatment. Galectin-1, a β-galactoside binding lectin, is up-regulated in the endothelium of tumors of different origin and has been shown to be the target for anginex, a powerful anti-angiogenic peptide wit...

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Bibliografische gegevens
Hoofdauteurs: Salomonsson, Emma, Thijssen, Victor L., Griffioen, Arjan W., Nilsson, Ulf J., Leffler, Hakon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077580/
https://ncbi.nlm.nih.gov/pubmed/21372130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.229096
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