The Anti-angiogenic Peptide Anginex Disrupts the Cell Membrane

Anginex is a synthetic beta-sheet peptide with anti-angiogenic and anti-tumor activity. When added to cultured endothelial cells at concentrations ranging from 2.5 μM to 25 μM, anginex induced cell death, which was reflected by a strong increase of subdiploid cells and fragments, loss of cellular AT...

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Bibliographic Details
Main Authors: Pilch, Jan, Franzin, Carla M., Knowles, Lynn M., Ferrer, Fernando J., Marassi, Francesca M., Ruoslahti, Erkki
Format: Artigo
Language:Inglês
Published: 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922962/
https://ncbi.nlm.nih.gov/pubmed/16403516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2005.12.006
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