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Beta-sheet is the bioactive conformation of the anti-angiogenic anginex peptide.
Anginex is a designed peptide 33mer that functions as a cytokine-like agent to inhibit angiogenesis. Although this short linear peptide has been shown by NMR and CD to form a nascent beta-sheet conformation in solution, the actual bioactive structure formed upon binding to its receptor on the surfac...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223486/ https://ncbi.nlm.nih.gov/pubmed/12708970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030295 |
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