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Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis s a target, a substrate, and a regulator
Several ribosomal proteins regulate p53 function via modulating MDM2. We recently found that RPS27L, a RPS27 like protein, is a direct p53 inducible target. Here we showed that RPS27 itself is a p53 repressible target. Furthermore, the N-terminal region of either RPS27L or RPS27 binds to MDM2 on the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077453/ https://ncbi.nlm.nih.gov/pubmed/21170087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.569 |
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