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Positive Autoregulation Delays the Expression Phase of Mammalian Clock Gene Per2

In mammals, cellular circadian rhythms are generated by a transcriptional-translational autoregulatory network that consists of clock genes that encode transcriptional regulators. Of these clock genes, Period1 (Per1) and Period2 (Per2) are essential for sustainable circadian rhythmicity and photic e...

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Détails bibliographiques
Auteurs principaux: Ogawa, Yukino, Koike, Nobuya, Kurosawa, Gen, Soga, Tomoyoshi, Tomita, Masaru, Tei, Hajime
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077398/
https://ncbi.nlm.nih.gov/pubmed/21533189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018663
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